Journal: ACS chemical neuroscience

Article Title: Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis

doi: 10.1021/acschemneuro.6b00208

Figure Lengend Snippet: Optimization and validation of etoposide-induced cell death in PC12 cells (passage 9–13). 50 × 103 cells/well. (a) Approximately 50% cell death was observed after 48 h. Four replicates per experiment. Values are represented as mean ± SD. Multiple t test, Holm-Sidak method, alpha = 5.000%, ****p < 0.0001. (b) Fluorescence measured after 48 h. Flupirtine at 3 μM concentration rescued the cells from apoptosis. Experiment repeated thrice. Values are represented as mean ± SD. Unpaired two-tailed t test, 95% CI, ****p < 0.0001 in comparison to vehicle. ####p < 0.0001 in comparison to etoposide treatment.

Article Snippet: 5 Etoposide (Chem-Impex International, 28435) was stored as a working stock solution of 150 μ g/mL at −20 °C for up to 3 months.

Techniques: Fluorescence, Concentration Assay, Two Tailed Test, Comparison

Journal: ACS chemical neuroscience

Article Title: Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis

doi: 10.1021/acschemneuro.6b00208

Figure Lengend Snippet: NGF differentiated PC12 cells show a statistically significant difference in sensitivity to apoptosis induced by etoposide between early and late passages at 72 h post insult. (a) Passage 10. Three replicates per experiment. Values are represented as mean ± SD. One-way ANOVA, Dunnett test, 95% CI. ****p < 0.0001. (b) Passage 17. Three replicates per experiment. Values are represented as mean ± SD. One-way ANOVA, Dunnett test, 95% CI. ****p < 0.0001. (c) Comparison of 72 h etoposide treatment in passage 10 and 17 PC12 cells differentiated using NGF. Unpaired two-tailed t test, 95% CI, ****p < 0.0001.

Article Snippet: 5 Etoposide (Chem-Impex International, 28435) was stored as a working stock solution of 150 μ g/mL at −20 °C for up to 3 months.

Techniques: Comparison, Two Tailed Test

Journal: Journal of Primary Care & Community Health

Article Title: Which Fecal Immunochemical Test Should I Choose?

doi: 10.1177/2150131917705206

Figure Lengend Snippet: FDA 510(k) Document Number and Test System/Manufacturer a for CLIA-Waived and Moderate Complexity FITs. b

Article Snippet: 17 , , Status iFOBT Princeton BioMeditech Corporation (10/19/2011) , 0.00 , K100817 , , , None.

Techniques: Diagnostic Assay, Control

Journal: Journal of Primary Care & Community Health

Article Title: Which Fecal Immunochemical Test Should I Choose?

doi: 10.1177/2150131917705206

Figure Lengend Snippet: CLIA-Waived and Moderate Complexity FITs Available for Purchase in United States as of July 22, 2016 With FDA Applicant, Respective 510(k) Document Number, Effective Date, and Accuracy in Human Studies. a

Article Snippet: 17 , , Status iFOBT Princeton BioMeditech Corporation (10/19/2011) , 0.00 , K100817 , , , None.

Techniques: Diagnostic Assay